A Monte Carlo approach to mean-square approximation

Monte Carlo algorithm for mean square approximation

Adjusting the frequency of mammography screening on the basis of genetic risk: Attitudes among women in the UK.

Purpose To explore public attitudes towards modifying frequency of mammography screening based on genetic risk. Methods Home-based interviews were carried out with a population-based sample of 942 women aged 18–74 years in the UK. Demographic characteristics and perceived breast cancer (BC) risk were examined as predictors of support for risk-stratified BC screening and of the acceptability of raised or lowered screening frequency based on genetic risk, using multivariate logistic regression. Results Over two-thirds of respondents (65.8%) supported the idea of varying screening frequency on the basis of genetic risk. The majority (85.4%) were willing to have more frequent breast screening if they were found to be at higher risk, but fewer (58.8%) were willing to have less frequent screening if at lower risk (t (956) = 15.6, p < 0.001). Ethnic minority status was associated with less acceptability of more frequent screening (OR = 0.40, 95% CI = 0.21–0.74), but there were no other significant demographic correlates. Higher perceived risk of BC was associated with greater acceptability of more frequent screening (OR = 1.71, 95%CI = 1.27–2.30). Conclusion Women were positive about adjusting the frequency of mammography screening in line with personal genetic risk, but it will be important to develop effective communication materials to minimise resistance to reducing screening frequency for those at lower genetic risk

Teaching A New Generation: The Differences Are Not Trivial

As organizational behavior learners apply managerial knowledge in classroom exercises or in the field, the hidden knowledge they hold of the cultural context of these applications works spontaneously to create meaning. This contextual knowledge is developed profoundly in our formative years; thus tacit experiential knowledge differs by generation. Today’s college-aged Millennials see organizational life and OB theory differently than yesterday’s Gen X, or Baby Boomer cohorts. These differences are revealed in an exercise using the vintage (1982) and current editions of the board game Trivial Pursuit. This activity asks learners to find the presence of generationally-cultivated knowledge in their daily lives and consider its effect on their use of OB theory. The experiential exercise is also linked to field interviews and other activities related to understanding generational differences in world view

Magnetodielectric coupling of infrared phonons in single crystal Cu2_{2}OSeO3_{3}

Reflection and transmission as a function of temperature have been measured on a single crystal of the magnetoelectric ferrimagnetic compound Cu$_{2}$OSeO$_{3}$ utilizing light spanning the far infrared to the visible portions of the electromagnetic spectrum. The complex dielectric function and optical properties were obtained via Kramers-Kronig analysis and by fits to a Drude-Lortentz model. The fits of the infrared phonons show a magnetodielectric effect near the transition temperature ($T_{c}\sim 60$~K). Assignments to strong far infrared phonon modes have been made, especially those exhibiting anomalous behavior around the transition temperature

A variable neurodegenerative phenotype with polymerase gamma mutation

mtDNA replication and repair, causes mitochondrial diseases including autosomal dominant progressive external ophthalmoplegia (PEO),1 childhood hepato-encephalopathy (Alpers– Huttenlocher syndrome), adult-onset spinocerebellar ataxia, and sensory nerve degeneration with dysarthria and ophthalmoparesis (SANDO)

Intentions to Prevent Weight Gain in Older and Younger Adults; The Importance of Perceived Health and Appearance Consequences

Objectives: This study investigates whether health and appearance consequences predict intentions to prevent weight gain and whether these relationships differ in younger versus older adults and in men versus women. Methods: UK adults aged 18-26 years (younger adults; n = 584) or > 45 years (older adults; n = 107) participated in an online survey. Logistic regression assessed associations between intentions to avoid gaining weight and age, gender as well as perceived negative consequences of weight gain for health and appearance. Co-variates were ethnicity, education, weight perception and perceived weight gain vulnerability. Interactions between age, gender and perceived health and appearance consequences of weight gain were also tested. Results: Perceived negative appearance consequences of weight gain predicted weight gain prevention intentions (OR = 9.3, p 0.01). Conclusion: Concerns about feeling unattractive predict intentions to prevent weight gain. However, health consequences of weight gain are only important motivators for older adults. Future research should identify ways to shift the focus of young people from appearance concerns towards the health benefits of maintaining a healthy weight

The synthesis of periodic sequential machines

Conversion of sequential machine into periodic one, with savings in logical element

Reliability in digital systems with asymmetrical failure modes

Reliability schemes in digital systems with asymmetrical failure mode